Azumolene
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $1150 | Check With Us |
| 250mg | $1750 | Check With Us |
| 500mg | $2625 | Check With Us |
: Cat #: V41122 CAS #: 64748-79-4 Purity ≥ 99%
Description: Azumolene is a potent muscle relaxant that inhibits the release of calcium from skeletal muscle sarcoplasmic reticulum.
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| Molecular Weight (MW) | 349.144 |
|---|---|
| Molecular Formula | C13H9BrN4O3 |
| CAS No. | 64748-79-4 |
| SMILES Code | O=C1NC(CN1/N=C/C2=NC=C(C3=CC=C(Br)C=C3)O2)=O |
| Synonyms | EU4093; EU-4093; EU 4093;Azumolene |
| Protocol | In Vivo | The effect of Azumolene (EU4093) on the twitch of the intact rat soleus preparation is nearly maximal at a dose of 20 mg/kg. This dose of Azumolene reduces the amplitude of the twitch to 31.9% of the control value. The contraction of intrafusal muscle as measured by the response of spindle afferent discharge is also reduced by Azumolene |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.8641 mL | 14.3207 mL | 28.6415 mL | 57.2830 mL |
| 5mM | 0.5728 mL | 2.8641 mL | 5.7283 mL | 11.4566 mL |
| 10mM | 0.2864 mL | 1.4321 mL | 2.8641 mL | 5.7283 mL |
| 20mM | 0.1432 mL | 0.7160 mL | 1.4321 mL | 2.8641 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
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Volume(start)
V1
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Concentration(final)
C2
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Volume(final)
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.