AZD2906
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $2650 | Check With Us |
| 250mg | $3950 | Check With Us |
| 500mg | $5925 | Check With Us |
: Cat #: V4249 CAS #: 1034148-15-6 Purity ≥ 98%
Description: AZD2906 is a novel, potent and selective glucocorticoid receptor (GR) agonist which increases micronucleated immature erythrocytes in the bone marrow of rats.
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- Physicochemical and Storage Information
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- Related Biological Data
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| Molecular Weight (MW) | 606.62 |
|---|---|
| Molecular Formula | C32H32F2N4O6 |
| CAS No. | 1034148-15-6 |
| Storage | -20℃ for 3 years in powder formrr |
| -80℃ for 2 years in solvent | |
| SMILES Code | FC(C=C1)=CC=C1N(N=C2)C(C2=C3)=CC=C3O[C@H](C4=CC=C(OC)N=C4)[C@H](C)NC(C5CC5) |
| Synonyms | AZD2906; AZD-2906; AZD 2906 |
| Protocol | In Vitro | AZD2906 is a selective glucocorticoid receptor (GR), with IC50s of 2.2, 0.3, 41.6 and 7.5 nM at GR in human, rat PBMC and human, rat whole blood, respectively. |
|---|---|---|
| In Vivo | AZD2906 (5, 25 mg/kg, p.o.) induces an accumulation of glycogen in the liver of rats, and exhibits cortical lymphocytic atrophy of a moderate to marked degree in the thymus of rats. AZD2906 (5, 25, 50 mg/kg, p.o.) increases micronucleated immature erythrocytes (MIE) in the bone marrow of rats after treatment for 2 days. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.6485 mL | 8.2424 mL | 16.4848 mL | 32.9696 mL |
| 5mM | 0.3297 mL | 1.6485 mL | 3.2970 mL | 6.5939 mL |
| 10mM | 0.1648 mL | 0.8242 mL | 1.6485 mL | 3.2970 mL |
| 20mM | 0.0824 mL | 0.4121 mL | 0.8242 mL | 1.6485 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
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Volume(start)
=
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.