AZD 4818

This product is for research use only, not for human use. We do not sell to patients.

AZD 4818
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
50mg$1600To Be Confirmed
100mg$2400To Be Confirmed
200mg$3600To Be Confirmed

Cat #: V12083 CAS #: 1003566-93-5 Purity ≥ 99%

Description: AZD 4818 (AZD-4818) is a novel and potent chemokine recptor CCR1 antagonist with the potential to be used for the treatment of COPD/chronic obstructive pulmonary disease.

References: Norman P. AZD-4818, a chemokine CCR1 antagonist: WO2008103126 and WO2009011653. Expert Opin Ther Pat. 2009;19(11):1629-1633.

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Molecular Weight (MW)567.46
Molecular FormulaC27H32Cl2N2O7
CAS No.1003566-93-5
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.7622 mL8.8112 mL17.6224 mL35.2448 mL
5mM0.3524 mL1.7622 mL3.5245 mL7.0490 mL
10mM0.1762 mL0.8811 mL1.7622 mL3.5245 mL
20mM0.0881 mL0.4406 mL0.8811 mL1.7622 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.