This product is for research use only, not for human use. We do not sell to patients.
| Size | Price | Stock |
|---|---|---|
| 5mg | $300 | 3-6 Days |
| 10mg | $550 | 3-6 Days |
| 25mg | $1050 | 3-6 Days |
| 50mg | $1850 | 3-6 Days |
: Cat #: V7698 CAS #: 1347304-18-0 Purity ≥ 99%
Description: Axitinib sulfoxide (also known as AG-028458; PF-03482595) is a primary and S-oxidized metabolite of Axitinib, an investigational anticancer drug. Axitinib (AG013736 and Inlyta) is a potent, orally bioavailable, small molecule and multi-targeted inhibitor TKI (tyrosine kinase inhibitor) that inhibits VEGFR1, VEGFR2, VEGFR3, PDGFRβ and c-Kit with IC50 of 0.1 nM, 0.2 nM, 0.1-0.3 nM, 1.6 nM and 1.7 nM in Porcine aorta endothelial cells, respectively.
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| Molecular Formula | C22H18N4O2S |
|---|---|
| CAS No. | 1347304-18-0 |
| SMILES Code | CNC(=O)c1ccccc1S(=O)c2ccc3c(c2)[nH]nc3/C=C/c4ccccn4 |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.