AVL-3288 (CCMI)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $1450 | Check With Us |
| 500mg | $2100 | Check With Us |
| 1g | $3150 | Check With Us |
: Cat #: V11955 CAS #: 917837-54-8 Purity ≥ 98%
Description: AVL-3288 (UCI-4083; UCI4083; CCMI; XY-4083; Anvylic-3288; AVL3288) is an orally bioavailable and selective allosteric modulator of the α7 nicotinic acetylcholine receptor (α7 nAChR) with neuroprotective effects.
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| Molecular Weight (MW) | 388.248 |
|---|---|
| Molecular Formula | C19H15Cl2N3O2 |
| CAS No. | 917837-54-8 |
| Synonyms | Anvylic-3288; UCI-4083; AVL-3288; UCI-4083; UCI4083; CCMI; XY-4083; Anvylic-3288; AVL3288; XY-4083; XY 4083; XY4083; UCI4083; UCI 4083; CCMI |
| Protocol | In Vitro | CCMI (Compound 6) is a potent and selective α7 nAChR-positive allosteric modulator, does not bind to or activate α7 nAChRs via the orthosteric site, and causes significant positive modulation of agonist-induced currents at α7 nAChRs |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.5757 mL | 12.8784 mL | 25.7567 mL | 51.5135 mL |
| 5mM | 0.5151 mL | 2.5757 mL | 5.1513 mL | 10.3027 mL |
| 10mM | 0.2576 mL | 1.2878 mL | 2.5757 mL | 5.1513 mL |
| 20mM | 0.1288 mL | 0.6439 mL | 1.2878 mL | 2.5757 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
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Volume(start)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
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C1
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V1
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C2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.