Aurora Kinase Inhibitor II
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $2600 | Check With Us |
| 250mg | $4200 | Check With Us |
| 500mg | $6300 | Check With Us |
: Cat #: V2345 CAS #: 331770-21-9 Purity ≥ 99%
Description: Aurora kinase inhibitor II is a novel , potent selective and ATP-competitive inhibitor of Aurora kinases.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 400.43 |
|---|---|
| Molecular Formula | C23H20N4O3 |
| CAS No. | 331770-21-9 |
| Protocol | In Vitro | Aurora kinase inhibitor-2 (Compound 1) shows excellent levels of Aurora A enzyme inhibition and is also effective in an MCF7 cellular anti-proliferative assay (IC50 value of 1.25 µM) |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.4973 mL | 12.4866 mL | 24.9732 mL | 49.9463 mL |
| 5mM | 0.4995 mL | 2.4973 mL | 4.9946 mL | 9.9893 mL |
| 10mM | 0.2497 mL | 1.2487 mL | 2.4973 mL | 4.9946 mL |
| 20mM | 0.1249 mL | 0.6243 mL | 1.2487 mL | 2.4973 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.