Aumitin | CAS 946293-78-3

Aumitin

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
1mg	$140	To Be Confirmed
5mg	$340	To Be Confirmed
10mg	$540	To Be Confirmed

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Cat #: V9156 CAS #: 946293-78-3 Purity ≥ 99%

Description: Aumitin is a diaminopyrimidine-based autophagy inhibitor that can suppress mitochondrial respiration by targeting complex I. Aumitin inhibits starvation- and rapamycin-induced autophagy in a dose-dependent fashion, with IC50 of 0.12 μM and 0.24 μM, respectively.

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Molecular Weight (MW)	429.901503562927
Molecular Formula	C24H20ClN5O
CAS No.	946293-78-3
Storage	Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Synonyms	Aumitin

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.3261 mL	11.6306 mL	23.2611 mL	46.5223 mL
5mM	0.4652 mL	2.3261 mL	4.6522 mL	9.3045 mL
10mM	0.2326 mL	1.1631 mL	2.3261 mL	4.6522 mL
20mM	0.1163 mL	0.5815 mL	1.1631 mL	2.3261 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.