Atropine sulfate monohydrate

This product is for research use only, not for human use. We do not sell to patients.

Atropine sulfate monohydrate
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Size Price Stock
5g$250Check With Us
10g$450Check With Us
20g$675Check With Us

Cat #: V1173 CAS #: 5908-99-6 Purity ≥ 98%

Description: Atropine sulfate monohydrate (Sulfatropinol; Tropintran; Atropette; Corbella), the sulfate salt and hydrated form of atropine, is a competitive and broad-spectrum antagonist of the muscarinic acetylcholine receptors.

References: Morhardt JE. Heart rates, breathing rates and the effects of atropine and acetylcholine on white-footed mice (Peromyscus sp.) during daily torpor. Comp Biochem Physiol. 1970 Mar 15;33(2):441-57.

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Molecular Weight (MW)694.83
Molecular Formula2(C17H23NO3).H2O.H2SO4
CAS No.5908-99-6
Storage-20℃ for 3 years in powder formrr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 139 mg/mL (200 mM)rr
Water: 139 mg/mL (200 mM)rr
Ethanol: 139 mg/mL (200 mM)
SMILES CodeO=S(O)(O)=O.O=C(OC1CC(N2C)CCC2C1)C(C3=CC=CC=C3)CO.[H]O[H]
SynonymsAtropine sulphate; Sulfatropinol; Tropintran; Atropette; Corbella; Atropine Sulfate; Atropine Sulfate hydrate
ProtocolIn VivoAtropine sulfate monohydrate (Tropine tropate; 10 mg/kg; intraperitoneal injection; once, for 40 minutes; Peromyscus sp.) May suppress arrhythmias that normally occur during numbness
Animal modelWhite-footed mice (Peromyscus sp.)
DosagesWhite-footed mice (Peromyscus sp.)
AdministrationIntraperitoneal injection; once, for 40 minutes
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.4392 mL7.1960 mL14.3920 mL28.7840 mL
5mM0.2878 mL1.4392 mL2.8784 mL5.7568 mL
10mM0.1439 mL0.7196 mL1.4392 mL2.8784 mL
20mM0.0720 mL0.3598 mL0.7196 mL1.4392 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.