ATI-2341
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 50mg | $1650 | To Be Confirmed |
| 100mg | $2550 | To Be Confirmed |
| 200mg | $3825 | To Be Confirmed |
: Cat #: V2585 CAS #: 1337878-62-2 Purity ≥ 98%
Description: ATI-2341 (ATI2341), a pepducin targeting the C-X-C chemokine receptor type 4 (CXCR4), is a novel and selective allosteric agonist of CXCR4 with anti-inflammatory and anticancer activity.
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| Molecular Weight (MW) | 2256.82 |
|---|---|
| Molecular Formula | C104H178N26O25S2 |
| CAS No. | 1337878-62-2 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 100 mg/mL (44.3 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: 2 mg/mL (0.88 mM) | |
| Synonyms | ATI2341; ATI 2341; ATI-2341 |
| Protocol | In Vivo | ATI-2341 induces CXCR4- and G protein-dependent signaling, receptor internalization, and chemotaxis in CXCR4-expressing cells. ATI-2341 has an EC50 value of 194 ± 16 nM and an intrinsic activity of 81 ± 4% in CCRF-CEM cells |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 0.4431 mL | 2.2155 mL | 4.4310 mL | 8.8620 mL |
| 5mM | 0.0886 mL | 0.4431 mL | 0.8862 mL | 1.7724 mL |
| 10mM | 0.0443 mL | 0.2216 mL | 0.4431 mL | 0.8862 mL |
| 20mM | 0.0222 mL | 0.1108 mL | 0.2216 mL | 0.4431 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.