Atglistatin

This product is for research use only, not for human use. We do not sell to patients.

Atglistatin
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$800Check With Us
500mg$1200Check With Us
1g$1800Check With Us

Cat #: V1958 CAS #: 1469924-27-3 Purity ≥ 98%

Description: Atglistatin is a highly potent and selective inhibitor of adipose triglyceride lipase (ATGL) with IC50 of 0.7 μM, it showed high selectivity over other key metabolic lipases.

References: Mayer N, et al. Development of small-molecule inhibitors targeting adipose triglyceride lipase. (2013) Nat Chem Biol. 9(12):785-7.

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Product Promise

Promise
Molecular Weight (MW)283.37
Molecular FormulaC17H21N3O
CAS No.1469924-27-3
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 57 mg/mL (201.2 mM)r
Water: <1 mg/mLr
Ethanol: 4 mg/mL (14.1 mM)
SMILES CodeCN(C1=CC=C(C=C1)C2=CC(NC(N(C)C)=O)=CC=C2)C
SynonymsAtglistatin
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.5290 mL17.6448 mL35.2896 mL70.5791 mL
5mM0.7058 mL3.5290 mL7.0579 mL14.1158 mL
10mM0.3529 mL1.7645 mL3.5290 mL7.0579 mL
20mM0.1764 mL0.8822 mL1.7645 mL3.5290 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.