AT-1001
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $800 | Check With Us |
| 500mg | $1200 | Check With Us |
| 1g | $1800 | Check With Us |
: Cat #: V11781 CAS #: 881851-50-9 Purity ≥ 98%
Description: AT-1001, formerly known as Larazotide Acetate, is a novel and synthetic peptide acting as a tight junction regulator and reverses leaky junctions to their normally closed state. It is being studied in people with celiac disease.
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- Physicochemical and Storage Information
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- Related Biological Data
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| Molecular Weight (MW) | 785.9 |
|---|---|
| Molecular Formula | C34H59N9O12 |
| CAS No. | 881851-50-9 |
| Synonyms | Larazotide Acetate; AT-1001; AT 1001; AT1001 |
| Protocol | In Vitro | Larazotide acetate (1-100 μM; 3 d) shows antiviral activity to varicella-zoster virus (VZV) with EC50s of 44.14 and 59.06 μM for strain OKA and 07-1, respectively |
|---|---|---|
| In Vivo | Larazotide acetate (250 μg; i.p. twice a week for 7 weeks) inhibits intestinal permeability in gluten-sensitive transgenic mice |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.2724 mL | 6.3621 mL | 12.7243 mL | 25.4485 mL |
| 5mM | 0.2545 mL | 1.2724 mL | 2.5449 mL | 5.0897 mL |
| 10mM | 0.1272 mL | 0.6362 mL | 1.2724 mL | 2.5449 mL |
| 20mM | 0.0636 mL | 0.3181 mL | 0.6362 mL | 1.2724 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.