Asoxime chloride
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $550 | Check With Us |
| 250mg | $1050 | Check With Us |
| 500mg | $1575 | Check With Us |
: Cat #: V11709 CAS #: 34433-31-3 Purity ≥ 99%
Description: Asoxime chloride (also known as HI-6; HI6) is a potent oxime reactivator agent that can be used for counteracting intoxication by nerve agents.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 359.21 |
|---|---|
| Molecular Formula | C14H16Cl2N4O3 |
| CAS No. | 34433-31-3 |
| Protocol | In Vivo | Asoxime dichloride (intramuscular injection into the rear limb; 2% and 0.2% of median lethal dose 15.6 and 1.56 mg/kg; 21 or 65 days) significantly improved vaccination efficacy as a dose-dependent manner when KLH is 1 mg/kg. A combination of HI-6 and keyhole limpet hemocyanin (KLH) produces a vaccination of almost the same efficacy as that for Freund's complete adjuvant |
|---|---|---|
| Animal model | Balb/c mice | |
| Dosages | 2% and 0.2% of median lethal dose 15.6 and 1.56mg/kg | |
| Administration | Intramuscular injection into the rear limb |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.7839 mL | 13.9194 mL | 27.8389 mL | 55.6777 mL |
| 5mM | 0.5568 mL | 2.7839 mL | 5.5678 mL | 11.1355 mL |
| 10mM | 0.2784 mL | 1.3919 mL | 2.7839 mL | 5.5678 mL |
| 20mM | 0.1392 mL | 0.6960 mL | 1.3919 mL | 2.7839 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.