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| Size | Price | Stock |
|---|---|---|
| 10mg | $230 | 3-6 Days |
| 25mg | $370 | 3-6 Days |
| 50mg | $560 | 3-6 Days |
| 100mg | $830 | 3-6 Days |
| 250mg | $1410 | 3-6 Days |
: Cat #: V41199 CAS #: 2055597-12-9 Purity ≥ 99%
Description: ASN007 (ASN-007) is a novel, potent, orally bioavailable and selective inhibitor of ERK1/2 with robust antitumor activity. It blocks ERK1/2 with an IC50 of 2 nM and the RAS/RAF/MEK/ERK (MAPK) signaling pathway. Regardless of the mutation's subtype, ASN007 exhibits strong preclinical activity in KRAS-driven models as well as BRAF mutant models, including melanoma resistant to RAF/MEK inhibitors.
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| Molecular Weight (MW) | 473.931006193161 |
|---|---|
| Molecular Formula | C22H25ClFN7O2 |
| CAS No. | 2055597-12-9 |
| Storage | Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
| Synonyms | ASN007; ASN 007; ASN-007 |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.1100 mL | 10.5501 mL | 21.1001 mL | 42.2002 mL |
| 5mM | 0.4220 mL | 2.1100 mL | 4.2200 mL | 8.4400 mL |
| 10mM | 0.2110 mL | 1.0550 mL | 2.1100 mL | 4.2200 mL |
| 20mM | 0.1055 mL | 0.5275 mL | 1.0550 mL | 2.1100 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.