Aristolactam I

This product is for research use only, not for human use. We do not sell to patients.

Aristolactam I
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$3710Check With Us
200mg$5565Check With Us
500mg$9390Check With Us

Cat #: V33182 CAS #: 13395-02-3 Purity ≥ 99%

Description: Aristolactam I (AL-I) is a major metabolite of aristolochic acid I (AA-I), and is able to form DNA adducts, thus causing renal damage.

References: Li J, et al. Toxicities of aristolochic acid I and aristololactam I in cultured renal epithelial cells. Toxicol In Vitro. 2010 Jun;24(4):1092-7.

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Molecular Weight (MW)293.27
Molecular FormulaC17H11NO4
CAS No.13395-02-3
SMILES CodeCOc1cccc2c1cc3NC(=O)c4cc5OCOc5c2c34
SynonymsAristololactam; Aristolactam I
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.4098 mL17.0491 mL34.0983 mL68.1965 mL
5mM0.6820 mL3.4098 mL6.8197 mL13.6393 mL
10mM0.3410 mL1.7049 mL3.4098 mL6.8197 mL
20mM0.1705 mL0.8525 mL1.7049 mL3.4098 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.