Argatroban (MD805; MCI9038; Argipidine)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 1g | $470 | In Stock |
| 2g | $800 | In Stock |
| 5g | $1350 | In Stock |
: Cat #: V1851 CAS #: 74863-84-6 Purity ≥ 98%
Description: Argatroban (MD-805; MCI-9038; Argipidine) is a potent and selective synthetic thrombin inhibitor with Ki ranging from 5 nM to 39 nM.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
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| Molecular Weight (MW) | 508.63 |
|---|---|
| Molecular Formula | C23H36N6O5S |
| CAS No. | 74863-84-6 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 9 mg/mL (17.7 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: 6 mg/mL (11.8 mM) | |
| SMILES Code | O=C(O)[C@H]1C[C@H](C)CCN1C([C@H](CCCNC(N)=N)NS(=O)(C2=CC=CC3=C2NCC(C)C3)=O)=O |
| Synonyms | MD-805; MD 805; MCI-9038; MCI9038; MCI9038; MD805; DK-7419; DK 7419; DK7419; GN1600; GN-1600; GN 1600; MMTQAP; MPQA; Novastan; OM 805; Slonnon; Argipidine. |
| Protocol | In Vitro | Argatroban (MD-805) may have a complementary effect for preventing thrombus formation without aggravating bleeding tendency because of its monotarget specificity to thrombin. Administration (0.5 to 2 micrograms/kg/min) of Argatroban (MD-805) is a safe anticoagulant for left heart bypass in repairs of traumatic aortic rupture associated with multiple organ injuries. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.9661 mL | 9.8303 mL | 19.6607 mL | 39.3213 mL |
| 5mM | 0.3932 mL | 1.9661 mL | 3.9321 mL | 7.8643 mL |
| 10mM | 0.1966 mL | 0.9830 mL | 1.9661 mL | 3.9321 mL |
| 20mM | 0.0983 mL | 0.4915 mL | 0.9830 mL | 1.9661 mL |
The molarity calculator equation
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The dilution calculator equation
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This equation is commonly abbreviated as: C1 V1 = C2 V2
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Step One: Enter information below
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Average weight of animals g
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Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.