AQ4

This product is for research use only, not for human use. We do not sell to patients.

AQ4
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
50mg$1250To Be Confirmed
100mg$1875To Be Confirmed
200mg$2812To Be Confirmed

Cat #: V7168 CAS #: 70476-63-0 Purity ≥ 98%

Description: AQ4 is a novel and potent topoisomerase II inhibitor and DNA intercalator with anticancer activities.

References: Luan X, et al. A Tumor Vascular-Targeted Interlocking Trimodal Nanosystem That Induces and Exploits Hypoxia. Adv Sci (Weinh). 2018 May 28;5(8):1800034. 

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Product Promise

Promise
Molecular Weight (MW)412.48
Molecular FormulaC22H28N4O4
CAS No.70476-63-0
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.4244 mL12.1218 mL24.2436 mL48.4872 mL
5mM0.4849 mL2.4244 mL4.8487 mL9.6974 mL
10mM0.2424 mL1.2122 mL2.4244 mL4.8487 mL
20mM0.1212 mL0.6061 mL1.2122 mL2.4244 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.