Apcin A

This product is for research use only, not for human use. We do not sell to patients.

Apcin A
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
1mg$120In Stock
5mg$210In Stock
10mg$310In Stock
25mg$560In Stock
50mg$930In Stock
100mg$1550In Stock
250mg$2410In Stock
email: [email protected]        [email protected]

Cat #: V2250 CAS #: 1683617-62-0 Purity ≥ 99%

Description: Apcin-A, an Apcin analogue, is an inhibitor (blocker/antagonist) of the anaphase promoting complex (APC). Apcin-A interacts strongly with Cdc20 and inhibits ubiquitination of Cdc20 substrates. Apcin-A may be utilized to prepare PROTAC CP5V.

Top Publications Citing Invivochem Products
Product Catalog 2022
Bulletin Board
Guide to Product Handling
Publications Citing InvivoChem Products
Product Promise
Promise
Molecular Weight (MW)342.609458446503
Molecular FormulaC10H14Cl3N5O2
CAS No.1683617-62-0
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

SynonymsApcin-A; Apcin A; 1683617-62-0; 3-Aminopropyl (2,2,2-trichloro-1-(pyrimidin-2-ylamino)ethyl)carbamate; starbld0000888; SCHEMBL22567019;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.9188 mL14.5939 mL29.1878 mL58.3755 mL
5mM0.5838 mL2.9188 mL5.8376 mL11.6751 mL
10mM0.2919 mL1.4594 mL2.9188 mL5.8376 mL
20mM0.1459 mL0.7297 mL1.4594 mL2.9188 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
=
Concentration
 
×
Volume
 
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
×
 
Volume(start)
V1
 
=
 
Concentration(final)
C2
 
×
 
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.