Apcin A

This product is for research use only, not for human use. We do not sell to patients.

Apcin A
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$1250In Stock
250mg$1950In Stock
500mg$2975In Stock

Cat #: V2250 CAS #: 1683617-62-0 Purity ≥ 98%

Description: Apcin-A is a novel and potent anaphase-promoting complex (APC) inhibitor.

References: Chi JJ, et al. A novel strategy to block mitotic progression for targeted therapy. EBioMedicine. 2019 Oct 25. pii: S2352-3964(19)30677-2.

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Promise
Molecular Weight (MW)342.61
Molecular FormulaC10H14Cl3N5O2
CAS No.1683617-62-0
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.9188 mL14.5939 mL29.1877 mL58.3754 mL
5mM0.5838 mL2.9188 mL5.8375 mL11.6751 mL
10mM0.2919 mL1.4594 mL2.9188 mL5.8375 mL
20mM0.1459 mL0.7297 mL1.4594 mL2.9188 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.