ANKRD-22-IN-1

This product is for research use only, not for human use. We do not sell to patients.

ANKRD-22-IN-1
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
1mg$130To Be Confirmed
5mg$270To Be Confirmed
10mg$430To Be Confirmed
email: sales@invivochem.com        sales@invivochem.cn

Cat #: V49933 CAS #: 1107710-62-2 Purity ≥ 99%

Description: AV023 is a potent ANKRD22 inhibitor. AV023 promotes the expansion of gastrointestinal mucosal epithelial stem cells, indirectly activates the Wnt classic pathway, and contributes to the recovery of damaged gastrointestinal mucosal tissue in the body (information disclosed in patent CN111205231B).

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Molecular Weight (MW)414.498005390167
Molecular FormulaC22H30N4O4
CAS No.1107710-62-2
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.4126 mL12.0628 mL24.1256 mL48.2511 mL
5mM0.4825 mL2.4126 mL4.8251 mL9.6502 mL
10mM0.2413 mL1.2063 mL2.4126 mL4.8251 mL
20mM0.1206 mL0.6031 mL1.2063 mL2.4126 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
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Volume(start)
V1
 
=
 
Concentration(final)
C2
 
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Volume(final)
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.