Anecortave Acetate

This product is for research use only, not for human use. We do not sell to patients.

Anecortave Acetate
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
500mg$950Check With Us
1g$1450Check With Us
5g$2175Check With Us

Cat #: V6438 CAS #: 7753-60-8 Purity ≥ 98%

Description: Anecortave Acetate is an angiostatic steroid used for proteomics research.

References: Clark AF. Mechanism of action of the angiostatic cortisene anecortave acetate. Surv Ophthalmol. 2007 Jan;52 Suppl 1:S26-34.

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Molecular Weight (MW)386.48
Molecular FormulaC23H30O5
CAS No.7753-60-8
SMILES CodeC1=2[C@@]3(C(=CC(CC3)=O)CC[C@H]1[C@@H]1CC[C@@]([C@@]1(C)CC2)(C(COC(=O)C)=O)O)C
SynonymsAl 3789; NSC 15475; NSC 24345; Retaane; Hydrocortisone Acetate EP Impurity E; Anecortave Acetate ; Anecortave;
ProtocolIn VivoAnecortave acetate (5 μl of a 10% suspension; Injected into eyes) significantly inhibits pathologic retinal angiogenesis and increases PAI-1 mRNA levels.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.5875 mL12.9373 mL25.8746 mL51.7491 mL
5mM0.5175 mL2.5875 mL5.1749 mL10.3498 mL
10mM0.2587 mL1.2937 mL2.5875 mL5.1749 mL
20mM0.1294 mL0.6469 mL1.2937 mL2.5875 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.