Ampicillin Trihydrate [D-(-)-α-Aminobenzylpenicillin]
This product is for research use only, not for human use. We do not sell to patients.
![Ampicillin Trihydrate [D-(-)-α-Aminobenzylpenicillin]](https://invivochem.net/wp-content/uploads/2023/05/6380462957338029581893740679-300x300.png "Ampicillin Trihydrate [D-(-)-α-Aminobenzylpenicillin]")
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| Size | Price | Stock |
|---|---|---|
| 25g | $400 | Check With Us |
| 50g | $600 | Check With Us |
| 100g | $900 | Check With Us |
: Cat #: V11234 CAS #: 7177-48-2 Purity ≥ 99%
Description: Ampicillin Trihydrate [D-(-)-α-Aminobenzylpenicillin] is a transpeptidase inhibitor used as a broad-spectrum beta-lactam antibiotic by preventing bacterial cell wall formation.
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| Molecular Weight (MW) | 403.45 |
|---|---|
| Molecular Formula | C16H25N3O7S |
| CAS No. | 7177-48-2 |
| SMILES Code | O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC([C@H](N)C3=CC=CC=C3)=O)N1C2=O)O.[H]O[H].[H]O[H].[H]O[H] |
| Synonyms | Aminobenzyl Penicillin; KS-R1; KS R1; Ukapen; KSR1; Polycillin;Amcill; Omnipen; Pentrexyl; |
| Protocol | In Vitro | Ampicillin trihydrate (D-(-)-α-Aminobenzylpenicillin trihydrate) inhibits the growth of E. coli of swine origin in a dose-dependent manner. The effective inhibitory concentration of Ampicillin trihydrate is 2.5 uG/mL[1]. |
|---|---|---|
| In Vivo | Ampicillin trihydrate (D-(-)-α-Aminobenzylpenicillin trihydrate) is very effective in alleviating the symptoms of hemorrhagic enteritis in a 11-week old pig[1]. Ampicillin trihydrate produces maximum concentrations in bile twice as high as in serum. The peak concentration of ampicillin after an oral dose is as twice as high in portal blood as in peripheral blood[2]. Ampicillin trihydrate provides neuroprotection against ischemia-reperfusion brain injury. Ampicillin trihydrate reduces the activities of MMPs and increases the expression level of GLT-1. Pretreatment with Ampicillin trihydrate significantly reduces medial hippocampal cell death following global forebrain ischemia[3]. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.4786 mL | 12.3931 mL | 24.7862 mL | 49.5724 mL |
| 5mM | 0.4957 mL | 2.4786 mL | 4.9572 mL | 9.9145 mL |
| 10mM | 0.2479 mL | 1.2393 mL | 2.4786 mL | 4.9572 mL |
| 20mM | 0.1239 mL | 0.6197 mL | 1.2393 mL | 2.4786 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.