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Amino-PEG5-alcohol

This product is for research use only, not for human use. We do not sell to patients.

Amino-PEG5-alcohol
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
500mg$400Check With Us
5g$1100Check With Us
10g$1650Check With Us
email: [email protected]        [email protected]

Cat #: V8602 CAS #: 34188-11-9 Purity ≥ 98%

Description: Amino-PEG5-alcohol is a PEG analogue containing an amino group with a hydroxyl group.

References: Nathanael Gray, et al. Bifunctional molecules for degradation of egfr and methods of use. WO2017185036A1.

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Molecular Weight (MW)237.29
Molecular FormulaC10H23NO5
CAS No.34188-11-9
SMILES CodeOCCOCCOCCOCCOCCN
SynonymsAmino-PEG5-alcohol
ProtocolIn VitroPROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM4.2143 mL21.0713 mL42.1425 mL84.2851 mL
5mM0.8429 mL4.2143 mL8.4285 mL16.8570 mL
10mM0.4214 mL2.1071 mL4.2143 mL8.4285 mL
20mM0.2107 mL1.0536 mL2.1071 mL4.2143 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
=
Concentration
 
×
Volume
 
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
×
 
Volume(start)
V1
 
=
 
Concentration(final)
C2
 
×
 
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.