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Amino-PEG3-alcohol

This product is for research use only, not for human use. We do not sell to patients.

Amino-PEG3-alcohol
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
1g$220Check With Us
5g$350Check With Us
10g$525Check With Us

Cat #: V5760 CAS #: 6338-55-2 Purity ≥ 98%

Description: Amino-PEG3-alcohol is a PEG analogue containing an amino group with a hydroxyl group.

References: An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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Product Promise

Promise
Molecular Weight (MW)149.19
Molecular FormulaC6H15NO3
CAS No.6338-55-2
SMILES CodeOCCOCCOCCN
SynonymsAmino-PEG3-alcohol
ProtocolIn VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM6.7029 mL33.5143 mL67.0286 mL134.0572 mL
5mM1.3406 mL6.7029 mL13.4057 mL26.8114 mL
10mM0.6703 mL3.3514 mL6.7029 mL13.4057 mL
20mM0.3351 mL1.6757 mL3.3514 mL6.7029 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.