Amino-PEG2-acid

This product is for research use only, not for human use. We do not sell to patients.

Amino-PEG2-acid
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$400Check With Us
500mg$680Check With Us
1g$1020Check With Us

Cat #: V7800 CAS #: 791028-27-8 Purity ≥ 98%

Description: Amino-PEG2-acid is a PEG analogue containing an amino group with a terminal carboxylic acid.

References: Antibody drug conjugate, intermediate, preparation method, pharmaceutical composition and uses thereof. WO2016197946A1.

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Molecular Weight (MW)177.20
Molecular FormulaC7H15NO4
CAS No.791028-27-8
SMILES CodeOC(CCOCCOCCN)=O
SynonymsAmino-PEG2-acid
ProtocolIn VitroADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM5.6433 mL28.2167 mL56.4334 mL112.8668 mL
5mM1.1287 mL5.6433 mL11.2867 mL22.5734 mL
10mM0.5643 mL2.8217 mL5.6433 mL11.2867 mL
20mM0.2822 mL1.4108 mL2.8217 mL5.6433 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.