AMI-1 disodium salt
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $550 | Check With Us |
| 500mg | $850 | Check With Us |
| 1g | $1275 | Check With Us |
: Cat #: V0388 CAS #: 20324-87-2 Purity ≥ 98%
Description: AMI-1 (AMI 1) disodium salt is a novel, cell-permeable and selective inhibitor of Histone Methyltransferase (HMT) with anti-inflammatory activity.
Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products
Product Promise
- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 548.45 |
|---|---|
| Molecular Formula | C21H14N2Na2O9S2 |
| CAS No. | 20324-87-2 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 100 mg/mL (182.3 mM)r |
| Water: 10 mg/mL (18.2 mM)r | |
| Ethanol: <1 mg/mL | |
| Solubility In Vivo | PBS: 22mg/mL |
| SMILES Code | O=C(NC1=CC2=CC(S(=O)([O-])=O)=CC(O)=C2C=C1)NC3=CC4=CC(S(=O)([O-])=O)=CC(O)=C4C=C3.[Na+].[Na+] |
| Synonyms | AMI-1 disodium salt; AMI 1; AMI1; AMI-1 |
| Protocol | In Vitro | IC50: 8.8 μM (PRMT1), 3.0 μM (yeast-Hmt1p) |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.8233 mL | 9.1166 mL | 18.2332 mL | 36.4664 mL |
| 5mM | 0.3647 mL | 1.8233 mL | 3.6466 mL | 7.2933 mL |
| 10mM | 0.1823 mL | 0.9117 mL | 1.8233 mL | 3.6466 mL |
| 20mM | 0.0912 mL | 0.4558 mL | 0.9117 mL | 1.8233 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.