AM-679

This product is for research use only, not for human use. We do not sell to patients.

AM-679
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5mg$220To Be Confirmed
10mg$280To Be Confirmed
50mg$760To Be Confirmed
email: sales@invivochem.com        sales@invivochem.cn

Cat #: V9466 CAS #: 1206880-66-1 Purity ≥ 99%

Description: AM679 is a potent and specific inhibitor of 5-lipoxygenase-activating protein (FLAP) with IC50 of 2 nM in a human membrane binding assay. AM679 significantly reduces respiratory syncytial virus-induced ocular lesions and the synthesis of ocular cysteinyl leukotrienes (CysLTs).

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Molecular Weight (MW)417.28
Molecular FormulaC20H20INO
CAS No.1206880-66-1
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

SynonymsAM-679 AM679AM 679 SCHEMBL503239 65KJ8P7M9DUNII-65KJ8P7M9D CHEMBL595092
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.3965 mL11.9824 mL23.9647 mL47.9294 mL
5mM0.4793 mL2.3965 mL4.7929 mL9.5859 mL
10mM0.2396 mL1.1982 mL2.3965 mL4.7929 mL
20mM0.1198 mL0.5991 mL1.1982 mL2.3965 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
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Volume(start)
V1
 
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.