Altretamine (ENT-50852)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 1g | $250 | Check With Us |
| 2g | $450 | Check With Us |
| 5g | $680 | Check With Us |
: Cat #: V2028 CAS #: 645-05-6 Purity ≥ 98%
Description: Altretamine (also known as Hexamethylmelamine, NSC13875, ENT50852, WR-95704) is an alkylating anticancer drug which also acts as a chemosterilant for male houseflies and other insects.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 210.28 |
|---|---|
| Molecular Formula | C9H18N6 |
| CAS No. | 645-05-6 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 15 mg/mL (71.3 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: 33 mg/mL (156.9 mM) | |
| Solubility In Vivo | Chemical Name: N2,N2,N4,N4,N6,N6-hexamethyl-1,3,5-triazine-2,4,6-triamine InChi Key: UUVWYPNAQBNQJQ-UHFFFAOYSA-N InChi Code: InChI=1S/C9H18N6/c1-13(2)7-10-8(14(3)4)12-9(11-7)15(5)6/h1-6H3 SMILES Code: CN(C)C1=NC(N(C)C)=NC(N(C)C)=N1 |
| Synonyms | NSC-13875; ENT-50852; RB-1515; WR-95704; NSC 13875; ENT 50852; RB 1515; WR 95704; NSC13875; ENT50852; RB1515; WR95704; Hexamethylmelamine, Hemel; Hexaloids; Hexalen; Hexastat; Hexinawas; HMM; HXM; |
| Protocol | In Vitro | Altretamine is an antineoplastic agent |
|---|---|---|
| In Vivo | Altretamine (100, 133 mg/kg, ip.) in combination with Irofulven, increases the antitumor effect in mice bearing MV522 cells |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 4.7556 mL | 23.7778 mL | 47.5556 mL | 95.1113 mL |
| 5mM | 0.9511 mL | 4.7556 mL | 9.5111 mL | 19.0223 mL |
| 10mM | 0.4756 mL | 2.3778 mL | 4.7556 mL | 9.5111 mL |
| 20mM | 0.2378 mL | 1.1889 mL | 2.3778 mL | 4.7556 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.