Aloxistatin (Loxistatin; E64d, NSC-694281)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $1550 | Check With Us |
| 1g | $2450 | Check With Us |
| 5g | $6200 | Check With Us |
: Cat #: V0698 CAS #: 88321-09-9 Purity ≥ 98%
Description: Aloxistatin (also known as E-64d, E-64c ethyl ester; EST, Loxistatin; NSC 694281) is a novel, potent, selective, irreversible, broad-spectrum and cell membrane-permeable cysteine protease inhibitor with anticoagulant activities.
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- Related Biological Data
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| Molecular Weight (MW) | 342.43 |
|---|---|
| Molecular Formula | C17H30N2O5 |
| CAS No. | 88321-09-9 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 68 mg/mL (198.6 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: 68 mg/mL (198.6 mM) | |
| Solubility In Vivo | 2% DMSO+corn oil: 5 mg/mL |
| SMILES Code | CCOC([C@@H]1[C@@H](C(N[C@H](C(NCCC(C)C)=O)CC(C)C)=O)O1)=O |
| Synonyms | E-64c ethyl ester; E64d; E64-d; EST; EP-453; EP453; EP 453; Aloxistatin; Loxistatin; NSC694281; NSC 694281; NSC-694281; E-64d; E 64d; E64 d |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.9203 mL | 14.6015 mL | 29.2030 mL | 58.4061 mL |
| 5mM | 0.5841 mL | 2.9203 mL | 5.8406 mL | 11.6812 mL |
| 10mM | 0.2920 mL | 1.4602 mL | 2.9203 mL | 5.8406 mL |
| 20mM | 0.1460 mL | 0.7301 mL | 1.4602 mL | 2.9203 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.