Aloesin
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $3075 | Check With Us |
| 200mg | $4610 | Check With Us |
| 500mg | $7780 | Check With Us |
: Cat #: V8001 CAS #: 30861-27-9 Purity ≥ 99%
Description: Aloesin is a novel and potent tyrosinase inhibitor.
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| Molecular Weight (MW) | 394.37 |
|---|---|
| Molecular Formula | C19H22O9 |
| CAS No. | 30861-27-9 |
| SMILES Code | CC(=O)CC1=CC(=O)c2c(C)cc(O)c([C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c2O1 |
| Synonyms | Aloesin, Aloe resin B, Aloeresin B |
| Protocol | In Vitro | Aloesin (0-10 μM; 48 h) inhibits the phosphorylation of the MAPK signaling pathway. Aloesin (0-10 μM; 48 h) promotes cell apoptosis in SKOV3 cells. Aloesin (0-10 μM; 48 h) arrest the cell cycle at S-phase in a dose-dependent manner in SKOV3 cells. Aloesin (0-40 μM, 24, 48, and 72 h) inhibits ovarian cancer cell growth in a dose- and time-dependent manner. |
|---|---|---|
| In Vivo | loesin (injection; 20 mg/kg or 40 mg/kg; once daily; 7 w) inhibits tumor growth in a Xenograft model of ovarian cancer. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.5357 mL | 12.6784 mL | 25.3569 mL | 50.7138 mL |
| 5mM | 0.5071 mL | 2.5357 mL | 5.0714 mL | 10.1428 mL |
| 10mM | 0.2536 mL | 1.2678 mL | 2.5357 mL | 5.0714 mL |
| 20mM | 0.1268 mL | 0.6339 mL | 1.2678 mL | 2.5357 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.