AKOS B018304

This product is for research use only, not for human use. We do not sell to patients.

AKOS B018304
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1250Check With Us
500mg$1850Check With Us
1g$2775Check With Us

Cat #: V3990 CAS #: 6308-22-1 Purity ≥ 98%

Description: AKOS B018304, an arylalkylidene derivative with polar substitution at para-position, is a potent inhibitor of chikungunya virus with low micro molar activity.

References: Jadav SS, et al. Thiazolidone derivatives as inhibitors of chikungunya virus. Eur J Med Chem. 2015 Jan 7;89:172-8.

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Product Promise

Promise
Molecular Weight (MW)266.30
Molecular FormulaC₁₀H₆N₂O₃S₂
CAS No.6308-22-1
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 10 mMr
Water: N/Ar
Ethanol: N/A
SMILES CodeO=C1NC(S/C1=C/C2=CC=CC=C2[N+]([O-])=O)=S
SynonymsAKOS B018304; AKOS-B018304; AKOSB018304; AKOS B018304; AKOS B 018304; AKOSB 018304; AKOSB-018304
ProtocolIn VitroAKOS B018304 (compound 6) is an arylalkylidene derivative, with polar substitution at para-position
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.7552 mL18.7758 mL37.5516 mL75.1033 mL
5mM0.7510 mL3.7552 mL7.5103 mL15.0207 mL
10mM0.3755 mL1.8776 mL3.7552 mL7.5103 mL
20mM0.1878 mL0.9388 mL1.8776 mL3.7552 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.