A-784168

This product is for research use only, not for human use. We do not sell to patients.

A-784168
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5mg$310To Be Confirmed
10mg$500To Be Confirmed
email: [email protected]        [email protected]

Cat #: V49742 CAS #: 824982-41-4 Purity ≥ 99%

Description: A-784168 is a potent and orally bioactive vanilloid receptor type 1 (TRPV1) inhibitor. Vanilloid receptor type 1 (TRPV1) is a ligand-gated non-selective cation channel thought to be an important integrator of a variety of pain stimuli like endogenous lipids, capsaicin, heat and low pH. . A-784168 has good CNS penetration.

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Molecular Weight (MW)479.3961
Molecular FormulaC19H15N3O3F6S
CAS No.824982-41-4
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.0860 mL10.4298 mL20.8596 mL41.7192 mL
5mM0.4172 mL2.0860 mL4.1719 mL8.3438 mL
10mM0.2086 mL1.0430 mL2.0860 mL4.1719 mL
20mM0.1043 mL0.5215 mL1.0430 mL2.0860 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.