A-366
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $400 | Check With Us |
| 250mg | $650 | Check With Us |
| 500mg | $975 | Check With Us |
: Cat #: V9842 CAS #: 1527503-11-2 Purity ≥ 98%
Description: A-366 (A366) is a novel, potent and peptide-competitive inhibitor of the histone methyltransferase G9a with anticancer activity.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 329.44 |
|---|---|
| Molecular Formula | C19H27N3O2 |
| CAS No. | 1527503-11-2 |
| SMILES Code | NC(C12CCC1)=NC3=C2C=C(OC)C(OCCCN4CCCC4)=C3 |
| Synonyms | A-366; A 366; A366 |
| Protocol | In Vitro | A-366 (0.01-10 μM; 14 days) induces differentiation and affects viability in MV4;11 cells. |
|---|---|---|
| In Vivo | A-366 (30 mg/kg; osmotic mini-pump; daily for 14 days) treatment of MV4;11 xenografts elicits growth inhibition. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.0355 mL | 15.1773 mL | 30.3545 mL | 60.7091 mL |
| 5mM | 0.6071 mL | 3.0355 mL | 6.0709 mL | 12.1418 mL |
| 10mM | 0.3035 mL | 1.5177 mL | 3.0355 mL | 6.0709 mL |
| 20mM | 0.1518 mL | 0.7589 mL | 1.5177 mL | 3.0355 mL |
The molarity calculator equation
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Volume
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The dilution calculator equation
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Volume(start)
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This equation is commonly abbreviated as: C1 V1 = C2 V2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.