AMP-PNP | CAS 72957-42-7

AMP-PNP

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Cat #: V41920 CAS #: 72957-42-7 Purity ≥ 99%

Description: AMP-PNP (Adenylyl-imidodiphosphate tetralithium), a non-hydrolysable analogue of ATP, is a novel Kir6 (KATP) channel blocker that inhibits fast axonal transport and stabilizes the interaction of membranous organelles with microtubules.

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Stock Solution Preparation
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Molecular Weight (MW)	529.9253
Molecular Formula	C10H13Li4N6O12P3
CAS No.	72957-42-7

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	1.8871 mL	9.4353 mL	18.8706 mL	37.7412 mL
5mM	0.3774 mL	1.8871 mL	3.7741 mL	7.5482 mL
10mM	0.1887 mL	0.9435 mL	1.8871 mL	3.7741 mL
20mM	0.0944 mL	0.4718 mL	0.9435 mL	1.8871 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.