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| Size | Price | Stock |
|---|---|---|
| 50mg | $50 | 3-6 Days |
| 100mg | $70 | 3-6 Days |
| 250mg | $100 | 3-6 Days |
| 500mg | $150 | 3-6 Days |
| 1g | $250 | 3-6 Days |
| 2g | $450 | 3-6 Days |
: Cat #: V2038 CAS #: 145375-43-5 Purity ≥ 98%
Description: Mitiglinide (also known as KAD-1229; S21403) is a Potassiun Channel blocker that is used as a blood glucose-lowering drug, it stimulates insulin secretion by closing the ATP-sensitive K+ channels in pancreatic beta-cells. Mitiglinide is thought to stimulate insulin secretion by closing the ATP-sensitive K(+) K(ATP) channels in pancreatic beta-cells. Mitiglinide may be potential useful for the treatment of type 2 diabetes.
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| Molecular Weight (MW) | 315.41 |
|---|---|
| Molecular Formula | C19H24NO3 |
| CAS No. | 145375-43-5 |
| Storage | -20℃ for 3 years in powder form |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: <1 mg/mL |
| Water:<1 mg/mL | |
| Ethanol: 2 mg/mL (2.99 mM) | |
| SMILES Code | O=C(O)[C@@H](CC1=CC=CC=C1)CC(N2C[C@]3([H])CCCC[C@]3([H])C2)=O |
| Synonyms | KAD-1229; KAD 1229; KAD1229; S 21403; Mitiglinide; Glufast. |
| Protocol | In Vitro | In vitro activity: Mitiglinide (KAD-1229; S21403) is a drug for the treatment of type 2 diabetes; it is a highly selective KATP channel antagonist. IC50 value: Target: KATP channel Mitiglinide is a hypoglycemic agent that closes adenosine triphosphate (ATP)-sensitive potassium channels (KATP channel s) in the pancreatic β-islet cells. Mitiglinide stimulates insulin secretion by stimulating Ca2+ influx. |
|---|
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.1705 mL | 15.8524 mL | 31.7048 mL | 63.4095 mL |
| 5mM | 0.6341 mL | 3.1705 mL | 6.3410 mL | 12.6819 mL |
| 10mM | 0.3170 mL | 1.5852 mL | 3.1705 mL | 6.3410 mL |
| 20mM | 0.1585 mL | 0.7926 mL | 1.5852 mL | 3.1705 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.