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FTO inhibitor 1

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FTO inhibitor 1
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
25mg$6503-6 Days
50mg$10003-6 Days
100mg$15003-6 Days
250mg$25003-6 Days
email: [email protected]        [email protected]

Cat #: V2479 CAS #: 2243736-37-8 Purity ≥ 99%

Description: FTO inhibitor 1 (first disclosed in WO 2018157842) is a novel and potent FTO (fat-mass- and obesity-associated protein) inhibitor with the potential to be used for treatment of leukemia. FTO is overexpressed in certain subtypes of AMLs and promotes leukemogenesis.

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CAS No.2243736-37-8
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
=
Concentration
 
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Volume
 
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
×
 
Volume(start)
V1
 
=
 
Concentration(final)
C2
 
×
 
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.