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TRX-0237 HBr

This product is for research use only, not for human use. We do not sell to patients.

TRX-0237 HBr
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
10mg$150To Be Confirmed
25mg$250To Be Confirmed
50mg$420To Be Confirmed
100mg$600To Be Confirmed
250mg$980To Be Confirmed
500mg$1450To Be Confirmed
email: [email protected]        [email protected]

Cat #: V2236 CAS #: 951131-15-0 Purity ≥ 99%

Description: TRX-0237 HBr (LMTX; LMT-X; TRX0237; Leuco-MTx; Hydromethylthionine mesylate; Leucomethylene Blue), the hydrobromide salt of TRX-0237 (in phase III clinical trials), is a novel and potent inhibitor of tau aggregation with potential use for the treatment of Alzheimer's disease (AD) and frontotemporal dementia. Hydromethylthionine showed pharmacological activity on brain structure and function as both monotherapy and as an add-on to symptomatic treatment in certain patients with Alzheimer's disease.

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CAS No.951131-15-0
SMILES Code CN(C)C1=CC(SC2=CC(N(C)C)=CC=C2N3)=C3C=C1.[H]Br.[H]Br
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.