This product is for research use only, not for human use. We do not sell to patients.
Size | Price | Stock |
---|---|---|
50mg | $60 | 3-6 Days |
100mg | $85 | 3-6 Days |
250mg | $115 | 3-6 Days |
500mg | $175 | 3-6 Days |
1g | $300 | 3-6 Days |
2g | $480 | 3-6 Days |
5g | $900 | 3-6 Days |
Cat #: V2086 CAS #: 51037-30-0 Purity ≥ 98%
Description: Acipimox (also known as Olbemox; K-9321; Olbetam) is a novel and potent niacin derivative used as a hypolipidemic agent. It is used in low doses and may have less marked adverse effects, although it is unclear whether the recommended dose is as effective as are standard doses of nicotinic acid. Acipimox inhibits the production of triglycerides by the liver and the secretion of VLDL, which leads indirectly to a modest reduction in LDL and increase in HDL. Long-term administration is associated with reduced mortality, but unwanted effects limit its clinical use. Adverse effects include flushing (associated with Prostaglandin D2), palpitations, and GI disturbances. Flushing can be reduced by taking aspirin 20-30 min before taking Acipimox. High doses can cause disorders of liver function, impair glucose tolerance and precipitate gout.
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Molecular Weight (MW) | 154.12 |
---|---|
Molecular Formula | C6H6N2O3 |
CAS No. | 51037-30-0 |
Storage | -20℃ for 3 years in powder form |
-80℃ for 2 years in solvent | |
Solubility In Vitro | DMSO: 31 mg/mL (201.1 mM) |
Water: <1 mg/mL | |
Ethanol: <1 mg/mL | |
Synonyms | Olbemox; K-9321; K9321; K 9321; Olbetam |
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 6.4885 mL | 32.4423 mL | 64.8845 mL | 129.7690 mL |
5mM | 1.2977 mL | 6.4885 mL | 12.9769 mL | 25.9538 mL |
10mM | 0.6488 mL | 3.2442 mL | 6.4885 mL | 12.9769 mL |
20mM | 0.3244 mL | 1.6221 mL | 3.2442 mL | 6.4885 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.