Ganciclovir Sodium
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 25g | $550 | Check With Us |
| 50g | $800 | Check With Us |
| 100g | $1200 | Check With Us |
: Cat #: V21502 CAS #: 107910-75-8 Purity ≥ 99%
Description: Ganciclovir sodium, an acyclovir analog, is a novel and potent antiviral drug used to treat or prevent cytomegalovirus (CMV) infections.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 277.21 |
|---|---|
| Molecular Formula | C9H12N5NaO4 |
| CAS No. | 107910-75-8 |
| SMILES Code | C1=NC2=C(N1COC(CO)CO)N=C(N=C2[O-])N.[Na+] |
| Protocol | In Vivo | Ganciclovir (BW 759) (50 mg/kg; i.p.; twice a day for five injections) significantly decreases white blood cells, red blood cells and platelets in newborn mice, and can diffuse into the brain and the perilymphatic space of the inner ear |
|---|---|---|
| Animal model | Non-inbred Oncins France 1 (OF1) mice and albino rats non-immunized for MCMV | |
| Dosages | 50 mg/kg | |
| Administration | Intraperitoneal injection, twice a day for five injections (mice) or 3 days (adult rats) (Pharmacokinetic Study) |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.6074 mL | 18.0369 mL | 36.0737 mL | 72.1475 mL |
| 5mM | 0.7215 mL | 3.6074 mL | 7.2147 mL | 14.4295 mL |
| 10mM | 0.3607 mL | 1.8037 mL | 3.6074 mL | 7.2147 mL |
| 20mM | 0.1804 mL | 0.9018 mL | 1.8037 mL | 3.6074 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.