Ganciclovir

This product is for research use only, not for human use. We do not sell to patients.

Ganciclovir
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Size Price Stock
50g$600Check With Us
100g$900Check With Us
200g$1350Check With Us

Cat #: V29193 CAS #: 82410-32-0 Purity ≥ 99%

Description: Ganciclovir (2'-Nor-2'-deoxyguanosine, BW-759) is a novel and potent herpes simplex virus (HSV) inhibitor.

References: Boujemla I, et al. Pharmacokinetics and tissue diffusion of ganciclovir in mice and rats. Antiviral Res. 2016;132:111-115.

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Molecular Weight (MW)255.23
Molecular FormulaC₉H₁₃N₅O₄
CAS No.82410-32-0
Synonyms2'-Nor-2'-deoxyguanosine, BW-759
ProtocolIn VivoGanciclovir (BW 759) (50 mg/kg; i.p.; twice a day for five injections) significantly decreases white blood cells, red blood cells and platelets in newborn mice, and can diffuse into the brain and the perilymphatic space of the inner ear
Animal modelNon-inbred Oncins France 1 (OF1) mice and albino rats non-immunized for MCMV
Dosages50 mg/kg
AdministrationIntraperitoneal injection, twice a day for five injections (mice) or 3 days (adult rats) (Pharmacokinetic Study)
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.9180 mL19.5902 mL39.1803 mL78.3607 mL
5mM0.7836 mL3.9180 mL7.8361 mL15.6721 mL
10mM0.3918 mL1.9590 mL3.9180 mL7.8361 mL
20mM0.1959 mL0.9795 mL1.9590 mL3.9180 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.