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Butoconazole Nitrate (RS35887)

This product is for research use only, not for human use. We do not sell to patients.

Butoconazole Nitrate (RS35887)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
2g$550Check With Us
5g$1050Check With Us
10g$1575Check With Us

Cat #: V16569 CAS #: 64872-77-1 Purity ≥ 98%

Description: Butoconazole Nitrate (RS-35887) is a synthetic imidazole analog with fungistatic/antifungal properties.

References: Anik ST, et al. Extreme vertexes design in formulation development: solubility of butoconazole nitrate in a multicomponent system. J Pharm Sci. 1981;70(8):897-900.

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Product Promise

Promise
Molecular Weight (MW)474.781
Molecular FormulaC19H18Cl3N3O3S
CAS No.64872-77-1
SynonymsRS35887, RS-35887, RS 35887; Gynazole-1, Mycelex-3, Butoconazole Nitrate
ProtocolIn VitroImidazoles generally inhibit the conversion of lanosterol to ergosterol, resulting in a change in fungal cell membrane lipid composition. This structural change alters cell permeability and, ultimately, results in the osmotic disruption or growth inhibition of the fungal cell
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.1062 mL10.5312 mL21.0623 mL42.1247 mL
5mM0.4212 mL2.1062 mL4.2125 mL8.4249 mL
10mM0.2106 mL1.0531 mL2.1062 mL4.2125 mL
20mM0.1053 mL0.5266 mL1.0531 mL2.1062 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.