Tavaborole

This product is for research use only, not for human use. We do not sell to patients.

Tavaborole
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5g$850Check With Us
10g$1450Check With Us
20g$2175Check With Us

Cat #: V15791 CAS #: 174671-46-6 Purity ≥ 98%

Description: Tavaborole (formerly known as AN-2690; AN2690; trade name Kerydin) is a topical antifungal medication approved by the US FDA in July 2014 for the treatment of onychomycosis, which is a fungal infection of the nail and nail bed.

References: Baker SJ, et al. Discovery of a new boron-containing antifungal agent, 5-fluoro-1,3-dihydro-1-hydroxy-2,1- benzoxaborole (AN2690), for the potential treatment of onychomycosis. J Med Chem. 2006 Jul 27;49(15):4447-50.

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Product Promise

Promise
Molecular Weight (MW)151.93
Molecular FormulaC7H6BFO2
CAS No.174671-46-6
SynonymsAN-2690, Tavaborole, AN 2690, AN2690,  Kerydin
ProtocolIn VitroTavaborole (AN-2690) shows an 8-fold increase in activity against C. neoformans, and an 8-fold increase in activity against A. fumigatus
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM6.5820 mL32.9099 mL65.8198 mL131.6396 mL
5mM1.3164 mL6.5820 mL13.1640 mL26.3279 mL
10mM0.6582 mL3.2910 mL6.5820 mL13.1640 mL
20mM0.3291 mL1.6455 mL3.2910 mL6.5820 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.