Pyrantel pamoate

This product is for research use only, not for human use. We do not sell to patients.

Pyrantel pamoate
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
50g$400Check With Us
100g$650Check With Us
200g$975Check With Us

Cat #: V13416 CAS #: 22204-24-6 Purity ≥ 99%

Description: Pyrantel pamoate, the pamoate salt of pyrantel, is a potent antinematodal and anthelmintic agent with a broad spectrum of activities.

References: Tritten L, et, al. In vitro and in vivo efficacy of Monepantel (AAD 1566) against laboratory models of human intestinal nematode infections. PLoS Negl Trop Dis. 2011 Dec;5(12):e1457.

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Molecular Weight (MW)594.68
Molecular FormulaC34H30N2O6S
CAS No.22204-24-6
ProtocolIn VitroPyrantel pamoate (10 nM-10 µM; 72 h) shows good anti-A. suum and (0-168.2 M; 72 h) anti-N. americanus activity
In VivoPyrantel pamoate (10 mg/kg; p.o.; single) reduces the worms in A. ceylanicum-infected hamsters, with the worm burden reduction of 87.2% and worm expulsion rate of 63.4%
Animal modelMale Syrian Golden hamsters (3-week-old; A. ceylanicum-infected)
Dosages10 mg/kg
AdministrationOral administration; single.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.6816 mL8.4079 mL16.8158 mL33.6315 mL
5mM0.3363 mL1.6816 mL3.3632 mL6.7263 mL
10mM0.1682 mL0.8408 mL1.6816 mL3.3632 mL
20mM0.0841 mL0.4204 mL0.8408 mL1.6816 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.