Mebendazole

This product is for research use only, not for human use. We do not sell to patients.

Mebendazole
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
2g$150Check With Us
5g$250Check With Us
10g$375Check With Us

Cat #: V16923 CAS #: 31431-39-7 Purity ≥ 98%

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Molecular Weight (MW)295.3
Molecular FormulaC16H13N3O3
CAS No.31431-39-7
SynonymsMebendazole; Vermox; Telmin; Pantelmin; Mebenvet; Telmin; Vermicol; Vermidil; Vermin; Vermox; Wormkuur
ProtocolIn VitroMebendazole (0.1 μM and 1 μM; 24 h) Disruption of microtubule aggregation and microtubule structure in 060919 glioblastoma multiforme (GBM) cells
In VivoMebendazole (50 mg/kg; p.o.; once daily for first 20 d and 5 d per week with 2 d off; 45) Inhibition of intracranial tumor growth in the homologous GL261 mouse model and 060919 human glioblastoma multiforme (GBM) xenograft mouse model
Animal modelC57BL/6 mice (5-6 weeks old) implanted with GL261 glioma cells and 060919 human glioblastoma multiforme (GBM)
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.3864 mL16.9319 mL33.8639 mL67.7277 mL
5mM0.6773 mL3.3864 mL6.7728 mL13.5455 mL
10mM0.3386 mL1.6932 mL3.3864 mL6.7728 mL
20mM0.1693 mL0.8466 mL1.6932 mL3.3864 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.