Doripenem Hydrate (S 4661)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
250mg	$450	Check With Us
500mg	$700	Check With Us
1g	$1050	Check With Us

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Cat #: V2008 CAS #: 364622-82-2 Purity ≥ 98%

Description: Doripenem Hydrate (also known as S-4661 and Finibax) is an ultra-broad-spectrum injectable and carbapenem class of beta-lactam antibiotic which is used to treat complicated intra-abdominal infections and complicated urinary tract infections.

References: Anderson DL. Doripenem. Drugs Today (Barc). 2006 Jun;42(6):399-404.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	438.52
Molecular Formula	C15H24N4O6S2.H2O
CAS No.	364622-82-2
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 36 mg/mL (82.1 mM)r
	Water: 26 mg/mL (59.3 mM)r
	Ethanol: <1 mg/mL
Synonyms	S-4661; S 4661; S4661; Doripenem Monohydrate; DRPM; Finibax; Doribax

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.2804 mL	11.4020 mL	22.8040 mL	45.6080 mL
5mM	0.4561 mL	2.2804 mL	4.5608 mL	9.1216 mL
10mM	0.2280 mL	1.1402 mL	2.2804 mL	4.5608 mL
20mM	0.1140 mL	0.5701 mL	1.1402 mL	2.2804 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.