Didanosine (Videx)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $545 | Check With Us |
| 1g | $850 | Check With Us |
| 5g | $2295 | Check With Us |
: Cat #: V1817 CAS #: 69655-05-6 Purity ≥ 98%
Description: Didanosine (also known as 2′,3′-dideoxyinosine, ddI, DDI; trade names Videx and Videx EC) is a potent reverse transcriptase inhibitor with an IC50 of 0.49 μM.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 236.23 |
|---|---|
| Molecular Formula | C10H12N4O3 |
| CAS No. | 69655-05-6 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 47 mg/mL (199.0 mM)r |
| Water:<1 mg/mLr | |
| Ethanol: <1 mg/mL | |
| Synonyms | 2',3'-Dideoxyinosine; Videx; Videx EC; ddI |
| Protocol | In Vitro | Didanosine (5, 10, 50, 100 ug/ml; 24, 48 h) shows no significant inhibition of cell proliferation in IEC-6 cells |
|---|---|---|
| In Vivo | Didanosine (100, 150 mg/kg; p.o.; daily for 7 days) decreases the length of duodenal and in jejunal villus in mouse | |
| Animal model | 30-40 g, male swiss mice | |
| Dosages | 100, 150 mg/kg | |
| Administration | P.o.; daily for 7 days |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 4.2332 mL | 21.1658 mL | 42.3316 mL | 84.6633 mL |
| 5mM | 0.8466 mL | 4.2332 mL | 8.4663 mL | 16.9327 mL |
| 10mM | 0.4233 mL | 2.1166 mL | 4.2332 mL | 8.4663 mL |
| 20mM | 0.2117 mL | 1.0583 mL | 2.1166 mL | 4.2332 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.