Abacavir sulfate (ABC)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 2g | $250 | Check With Us |
| 10g | $445 | Check With Us |
| 20g | $667 | Check With Us |
: Cat #: V1826 CAS #: 188062-50-2 Purity ≥ 98%
Description: Abacavir (formerly also known as ABC, or 1592U89; trade names: Ziagen; Epzicom) is a commonly used nucleoside analogue of the NRTI class with potent antiviral activity against HIV-1.
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- Physicochemical and Storage Information
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- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 335.35 |
|---|---|
| Molecular Formula | C14H18N6O.1/2 H2O4S |
| CAS No. | 188062-50-2 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: <1 mg/mLr |
| Water: 36 mg/mL (107.4 mM)r | |
| Ethanol: <1 mg/mL | |
| Synonyms | Abacavir Hemisulfate; ABC sulfate; 1592U89; ABC, Ziagen; Epzicom; 1592 U89; 1592 U89; 1592U-89; 1592-U89; 1592 U 89. |
| Protocol | In Vivo | Abacavir (0-7.5 μg/mL, 100 μL, intrascrotal administration; 100 and 200 mg/kg, p.o.; 4 h) sulfate dose-dependently promoted thrombus formation |
|---|---|---|
| Animal model | Male mice (9-weeks old, 22-30 g) - wild-type (WT) C57BL/6 or homozygous knockout (P2rx7 KO, B6.129P2-P2rx7tm1Gab/J) | |
| Dosages | 2.5, 5 and 7.5 μg/mL, 100 μL or 100 and 200 mg/kg | |
| Administration | Intrascrotal or oral administration for 4 h |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.9820 mL | 14.9098 mL | 29.8196 mL | 59.6392 mL |
| 5mM | 0.5964 mL | 2.9820 mL | 5.9639 mL | 11.9278 mL |
| 10mM | 0.2982 mL | 1.4910 mL | 2.9820 mL | 5.9639 mL |
| 20mM | 0.1491 mL | 0.7455 mL | 1.4910 mL | 2.9820 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.