Nuezhenide

This product is for research use only, not for human use. We do not sell to patients.

Nuezhenide
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$750To Be Confirmed
200mg$1125To Be Confirmed
500mg$1900To Be Confirmed

Cat #: V34256 CAS #: 39011-92-2 Purity ≥ 99%

Description: Specnuezhenide ((8E)-Nuezhenide) is natural product of the iridoid class isolated from the fruits of Ligustrum lucidum.

References: Ma C, et al. Specnuezhenide Decreases Interleukin-1β-Induced Inflammation in Rat Chondrocytes and Reduces Joint Destruction in Osteoarthritic Rats.Front Pharmacol. 2018 Jun 28;9:700.

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Product Promise

Promise
Molecular Weight (MW)686.66
Molecular FormulaC31H42O17
CAS No.39011-92-2
SynonymsNuezhenide
ProtocolIn VitroSpecnuezhenide (0.2-5.0 μg/mL) significantly decreases the mRNA expression of VEGFA induced by CoCl2 as a dose-dependent manner in ARPE-19 cells.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.4563 mL7.2816 mL14.5632 mL29.1265 mL
5mM0.2913 mL1.4563 mL2.9126 mL5.8253 mL
10mM0.1456 mL0.7282 mL1.4563 mL2.9126 mL
20mM0.0728 mL0.3641 mL0.7282 mL1.4563 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.