Carbimazole

This product is for research use only, not for human use. We do not sell to patients.

Carbimazole
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
50g$450Check With Us
100g$750Check With Us
200mg$1125Check With Us

Cat #: V17547 CAS #: 22232-54-8 Purity ≥ 99%

Description: Carbimazole (Neomercazole; Neo-Tireol; Carbimazole) is a suppressor of thyroid hormone production that has been used for treating hyperthyroidism.

References: Nakashima, T. and A. Taurog, Rapid conversion of carbimazole to methimazole in serum; evidence for an enzymatic mechanism. Clin Endocrinol (Oxf), 1979. 10(6): p. 637-48.

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Molecular Weight (MW)186.229
Molecular FormulaC7H10N2O2S
CAS No.22232-54-8
SynonymsNeomercazole; Neo-Tireol; Carbimazole
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM5.3697 mL26.8487 mL53.6973 mL107.3947 mL
5mM1.0739 mL5.3697 mL10.7395 mL21.4789 mL
10mM0.5370 mL2.6849 mL5.3697 mL10.7395 mL
20mM0.2685 mL1.3424 mL2.6849 mL5.3697 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.