Formestane (CGP-32349)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
5g | $350 | Check With Us |
10g | $525 | Check With Us |
20g | $787 | Check With Us |
Cat #: V1801 CAS #: 566-48-3 Purity ≥ 98%
Description: Formestane (formerly also known as CGP-32349, NSC 282175) is a second generation, selective, orally bioactive and synthetic steroidal aromatase inhibitor with an IC50 of 80 nM.
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Molecular Weight (MW) | 302.41 |
---|---|
Molecular Formula | C19H26O3 |
CAS No. | 566-48-3 |
Storage | -20℃ for 3 years in powder formr |
-80℃ for 2 years in solvent | |
Solubility In Vitro | DMSO: 61 mg/mL (201.7 mM)r |
Water: <1 mg/mLr | |
Ethanol:<1 mg/mL | |
Synonyms | CGP-32349, NSC282175; NSC-282175; NSC 282175; CGP32349; CGP 32349; CGP-32349; 4OHA; 4OHAD; Formestane; Lentaron. |
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 3.3068 mL | 16.5338 mL | 33.0677 mL | 66.1354 mL |
5mM | 0.6614 mL | 3.3068 mL | 6.6135 mL | 13.2271 mL |
10mM | 0.3307 mL | 1.6534 mL | 3.3068 mL | 6.6135 mL |
20mM | 0.1653 mL | 0.8267 mL | 1.6534 mL | 3.3068 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.