Benazepril HCl (CGS14824A)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
2g	$200	Check With Us
10g	$750	Check With Us
20g	$1125	Check With Us

: [email protected] [email protected]

Cat #: V1787 CAS #: 86541-74-4 Purity ≥ 98%

Description: Benazepril HCl (formerly CGS 14824A; CGS-14824-A; Briem; Cibacène; Cibacen; Labopal; Lotensin), the hydrochloride salt of Benazepril which is a prodrug that can be metabolized to its active form benazeprilat, is a potent angiotensin I converting enzyme (ACE) inhibitor that has been widely used primarily in treatment of hypertension.

References: Hou FF, et al. Efficacy and safety of benazepril for advanced chronic renal insufficiency. N Engl J Med. 2006 Jan 12;354(2):131-40.

Top Publications Citing Invivochem Products

Product Catalog 2022

Guide to Product Handling

Publications Citing InvivoChem Products

Product Promise

Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	460.95
Molecular Formula	C24H28N2O5.HCl
CAS No.	86541-74-4
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 92 mg/mL (199.6 mM)r
	Water: 19 mg/mL (41.2 mM)r
	Ethanol: 92 mg/mL (199.6 mM)
Synonyms	CGS 14824A HCl; CGS14824A; Briem; CGS-14824-A; CGS-14824A; CGS-14824 A; Cibacène; Cibacen; Labopal; Lotensin

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.1694 mL	10.8472 mL	21.6943 mL	43.3887 mL
5mM	0.4339 mL	2.1694 mL	4.3389 mL	8.6777 mL
10mM	0.2169 mL	1.0847 mL	2.1694 mL	4.3389 mL
20mM	0.1085 mL	0.5424 mL	1.0847 mL	2.1694 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.